Technically, yes you could install these tiles in an offset of ashlar brick pattern. To do this will take some work on your end, and you would need to glue the tiles down. First, you would need to cut the tabs off all the tiles. Next, you would use a pressure sensitive glue and follow the install instructions for how to use it and what trowel to use. You would then place and cut the tiles in the desired configuration. To figure out the number of tiles needed, please feel free to contact one of our Flooring Heroes via chat, phone, or email, and they would be more than happy to assist.